Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2538242 | Fitoterapia | 2016 | 4 Pages |
Abstract
Three new xanthones, cylindroxanthones A–C (1–3), were isolated from the stem bark of Garcinia cylindrocarpa. The structures were established on the basis of spectroscopic analysis. The molecular structure of 1 was unequivocally confirmed by single-crystal X-ray diffraction analysis. These three xanthones were evaluated regarding their cytotoxicity against KB, HeLa S-3, HT-29, MCF-7, and Hep G2 cancer cell lines. Compound 1 exhibited good cytotoxicity against KB cell with IC50 value of 2.36 μM.
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Pharmacology, Toxicology and Pharmaceutical Science
Pharmacology
Authors
Edwin Risky Sukandar, Taslim Ersam, Sri Fatmawati, Pongpun Siripong, Thammarat Aree, Santi Tip-pyang,