Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2538245 | Fitoterapia | 2016 | 6 Pages |
Abstract
Two new clerodane diterpenoids (1–2), one new clerodane diterpenoid alkaloid (3), as well as thirteen known compounds were isolated from Croton crassifolius. The structures of new compounds were established by a combination of spectroscopic methods, including HRMS, 1H NMR, 13C NMR, 1H 1H COSY, HSQC, HMBC, NOESY and X-ray crystallographic analysis. Compound 3 is firstly reported as the clerodane-type diterpenoid alkaloid in natural products. All of the compounds were evaluated for in vitro cytotoxic activities against CT26.WT cell using the MTT method.
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Authors
Maosong Qiu, Di Cao, Youheng Gao, Shuhua Li, Jinping Zhu, Bao Yang, Lian Zhou, Yuan Zhou, Jing Jin, Zhongxiang Zhao,