| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2538258 | Fitoterapia | 2015 | 4 Pages |
Two new compounds, 2S-hydroxyl-jiadifenolide (1) and jiadifenlactone acid (2), and eight known compounds were isolated from the fruits of Illicium jiadifengpi. Their structures were analysed using several spectroscopic techniques, including 1D-, 2D-NMR and HR-ESI-MS experiments. The anti-hepatitis B virus (HBV) activities of the isolates were evaluated via HBV transfection of the Hep G2.2.15 cell line. The inhibitory rates of the most active compounds, compounds 4 and 5, on the HBeAg and HBsAg expression were 28.85 ± 3.15% and 17.53 ± 1.81% and 37.93 ± 2.74% and 23.47 ± 9.52% at concentrations of 64.94 μM and 61.35 μM, respectively.
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