Article ID Journal Published Year Pages File Type
2538260 Fitoterapia 2015 5 Pages PDF
Abstract

Three new brasilane-type sesquiterpenoids, brasilanes A–C (1–3), together with two new alkane derivatives, colisiderin A (4) and 7(E),9(E)-undecandiene-2,4,5-triol (5), were isolated from cultures of the basidiomycete Coltricia sideroides. Their structures were elucidated by NMR and MS data analyses. The absolute configuration of 4 was determined by TDDFT ECD calculations while brasilane-type sesquiterpenoids were isolated from cultures of mushroom for the first time. Compounds 2 and 4 showed weak cytotoxicities against HL-60 and SW480, respectively.

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Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology
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