Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2538274 | Fitoterapia | 2015 | 6 Pages |
Abstract
Seven new drimane-type sesquiterpenoids, sulphureuines B–H (1–7), together with four known compounds (8–11), were obtained from cultures of mushroom Laetiporus sulphureus. All of these compounds were tested for their cytotoxicities against five human cancer cell lines (HL-60, SMMC-721, A-549, MCF-7, SW-480), compound 10 showed potent cytotoxic activity against HL-60, SMMC-721, A-549, SW-480, with IC50 values of 37.5, 14.8, 15.6, and 36.1 μM, respectively.
Graphical abstractFigure optionsDownload full-size imageDownload high-quality image (221 K)Download as PowerPoint slide
Keywords
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Pharmacology
Authors
Jiang-Bo He, Jian Tao, Xi-Song Miao, Wei Bu, Shen Zhang, Ze-Jun Dong, Zheng-Hui Li, Tao Feng, Ji-Kai Liu,