| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2538294 | Fitoterapia | 2015 | 7 Pages |
Abstract
Bioassay guided fractionation of Hypericum riparium leaves extract has resulted in the isolation and characterization of three new compounds namely chipericumin E (1), hyperenone C (3), and hyperixanthone (5), together with twenty known compounds. Their structures were elucidated based on comprehensive interpretation of spectroscopic and spectrometric data. Compounds 1–4, and 6–8 displayed moderate antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) and cytotoxic effects on the human gastric cell line BGC-823 with IC50 values ranging from 6.54 to 18.50 μM.
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Authors
Michel Feussi Tala, Ferdinand Mouafo Talontsi, Guang-Zhi Zeng, Hippolyte Kamdem Wabo, Ning-Hua Tan, Michael Spiteller, Pierre Tane,