Article ID Journal Published Year Pages File Type
2538295 Fitoterapia 2015 7 Pages PDF
Abstract

Phytochemical examination of the leaves and stems of Viscum articulatum resulted in the isolation of three pairs of new flavanone glycosides, 2R/2S-viscarticulide A–C (1a/1b–3a/3b), together with eight known compounds (7–14). Their structures were established by extensive spectroscopic data analyses. The diastereoisomers were separated by HPLC on a chiral phase and the absolute configuration at C-2 was determined by circular dichroism (CD) spectra. The protective effects of compounds 1–3 against H2O2-induced cytotoxicity with EA.hy926 cells were tested. The results showed that compounds 1–3 improved the survival of EA.hy926 cells after H2O2 exposure at the tested concentrations.

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