Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2538446 | Fitoterapia | 2015 | 6 Pages |
Abstract
Four new nardosinane-type sesquiterpenoids nardosinanones F–I (1–2, 4–5), along with eight known sesquiterpenoids (3, 6–12) were isolated from the underground parts of Nardostachys chinensis Batal. Their structures were elucidated on the basis of extensive spectroscopic analysis. Compounds 1 and 2 were new nardosinane sesquiterpenoids processing a rare 4,11-epoxy group in nature. In addition, compounds 1, 5–7, 11 and 12 showed protective effects on neonatal rat cardiomyocyte injury induced by hydrogen peroxide.
Graphical abstractFigure optionsDownload full-size imageDownload high-quality image (129 K)Download as PowerPoint slide
Keywords
Related Topics
Health Sciences
Pharmacology, Toxicology and Pharmaceutical Science
Pharmacology
Authors
Jin-Bo Zhang, Ming-Li Liu, Chang Li, Yan Zhang, Yi Dai, Xin-Sheng Yao,