| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2538610 | Fitoterapia | 2014 | 4 Pages |
Abstract
Three new furoquinoline alkaloids, leptanoines A–C (1–3) along with three known compounds (4–6) were isolated from the leaves of Evodia lepta. Their structures were identified by interpretation of their spectroscopic data as well as comparison with those reported in the literature. In addition, all isolated compounds were evaluated for their acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) activities. Compound 4 showed the highest inhibitory activity towards BChE with an IC50 value of 47.9 μM. On the other hand, Compound 5 showed the highest inhibitory activity towards AChE with an IC50 value of 69.1 μM.
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Authors
Jirapast Sichaem, Apapond Jirasirichote, Krittakorn Sapasuntikul, Suttira Khumkratok, Pattara Sawasdee, Thi My Lien Do, Santi Tip-pyang,