| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2538631 | Fitoterapia | 2013 | 5 Pages |
Abstract
Five new 8-9′ linked neolignans conchigeranals A–E (1–5), together with three known compounds galanganal (6), galanganols A (7) and B (8), were isolated from the whole plant of Alpinia conchigera. Their structures were established by spectroscopic analysis, including 2D-NMR spectroscopic techniques. Cytotoxicities of compounds 1–8 were tested against two cancer cell lines A549 and Hela. Results showed that 4, 5, 7 and 8 exhibited cytotoxicity against A549 with the IC50 values of 12.36, 9.72, 10.26, 13.05 μg/ml, respectively, and 1–8 against Hela with the IC50 values from 1.53 to 5.29 μg/ml.
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Authors
Jun-Ju Xu, Guang-Zhi Zeng, Sheng-Chao Yang, Yong Shen, Ning-Hua Tan,