Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2538635 | Fitoterapia | 2013 | 6 Pages |
Abstract
Five new secoiridoids, nuzhenal C (1), 6'-O-trans-cinnamoyl iso-8-epikingisidic acid (2), ligulucidumosides A (3), B (4), and C (5), were obtained from the fruits of Ligustrum lucidum Ait. Their structures were elucidated by chemical and spectroscopic methods (UV, IR, HRESI-TOF-MS, 1D and 2D NMR). Among them, compound 3 is the first 1-OCH3 substituent secoiridoid obtained from plant kingdom. Furthermore, activity screening results showed that all of the isolates had triglyceride accumulation inhibitory effects in HepG2 cells.
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Authors
Yi Zhang, Lili Liu, Jing Gao, Chunhua Wu, Lifeng Han, Erwei Liu, Pingping Shi, Xiumei Gao, Tao Wang,