Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2538715 | Fitoterapia | 2012 | 6 Pages |
Abstract
A phytochemical investigation of the whole plants of Ajuga decumbens led to the isolation of three new (1, 2a, and 2b) and three known (3a−3c) neo-clerodane diterpenes. Their structures were elucidated by spectroscopic data analysis (IR, ESIMS, HR-ESIMS, 1D and 2D NMR), and the structure of 1 was confirmed by X-ray crystallography. The inhibitory activities on LPS-induced NO production of the six diterpenes were evaluated and compounds 2a, 2b, and 3a showed inhibitory effects.
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Authors
Zhanping Sun, Yushan Li, Da-qing Jin, Ping Guo, Haibin Song, Jing Xu, Yuanqiang Guo, Lei Zhang,