| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2538726 | Fitoterapia | 2012 | 5 Pages |
Five novel compounds were isolated from the water extract of Tabebuia avellanedae, and their structures were established by analysis of NMR spectroscopy and mass spectrometry. Compounds 1–5 at 25 μM showed strong inhibitory activity on the inflammatory cytokine, tumor-necrosis factor-α and interleukin-1β production in cultured human myeloma THP-1 cells co-stimulated with lipopolysaccharide without any significant cytotoxicity, and their anti-allergic and antioxidant activities were evaluated.
Graphical abstractFive novel compounds were isolated from the water extract of Tabebuia avellanedae, and these compounds at 25 μM showed strong anti-inflammatory activities.Figure optionsDownload full-size imageDownload high-quality image (131 K)Download as PowerPoint slide
