Article ID Journal Published Year Pages File Type
2538736 Fitoterapia 2012 5 Pages PDF
Abstract

A new meroterpene, psoracorylifol F (1), was isolated from Psoralea corylifolia fruits, along with two known meroterpenes (2 and 3), guided by TLC bioautography against O2− radicals. The structure of 1 was elucidated by means of NMR, HRESIMS, and X-ray crystallographic analysis. All the three metroterpenes possessed potential inhibitory activity against LPS-induced NO production in RAW 264.7 cells with IC50 values ranging from 7.71 to 27.63 μM.

Graphical abstractFigure optionsDownload full-size imageDownload high-quality image (153 K)Download as PowerPoint slide

Related Topics
Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology
Authors
, , , , , ,