| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2538757 | Fitoterapia | 2012 | 6 Pages |
Abstract
The diphenyl ether, lobarin (1) (syn. lobariol carboxylic acid) related to lobaric acid was isolated for the first time as a natural product along with five known compounds from Stereocaulon halei, a fruticose lichen collected in Indonesia. The structure of lobarin was elucidated by spectroscopic data analysis and its most stable conformers were determined by molecular mechanic dynamic calculations. A marked superoxide anion scavenging was found for compound 1 while no cytotoxicity on the B16 murine melanoma and HaCaT human keratinocyte cell lines was observed.
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Authors
Friardi Ismed, Françoise Lohézic-Le Dévéhat, Olivier Delalande, Sourisak Sinbandhit, Amri Bakhtiar, Joël Boustie,