Chemical constituents of the aerial part of Derris elliptica

A new coumaronochromone, 6,4′-dihydroxy-7,5' -dimethoxy-coumaronochromone (1), together with eleven known flavonoids (2–12) were isolated from the ethanol extract of the aerial part of Derris elliptica. Their structures were elucidated on the basis of spectroscopic analysis. Compounds 2, 4, 7, 8 and 9 exhibited moderate insecticidal activities against larvae of Aedes albopictus. All compounds showed strong cytotoxic activities against Spodoptera litura (SL) and Trichoplusia ni BTI-Tn-5B1-4 (Hi-5) cells comparison to positive control of rotenone.

Graphical abstractA new coumaronochromone, 6,4'-dihydroxy-7,5'-dimethoxy-coumaronochromone (1), with eleven known flavonoids (2-12) were isolated from Derris elliptica. All compounds showed strong cytotoxic activities to rotenone and five of those exhibited larvicidal activities.Figure optionsDownload full-size imageDownload high-quality image (38 K)Download as PowerPoint slide