Synthetic and green vegetable isothiocyanates target red blood leukemia cancers

Isothiocyanates (ITCs), the breakdown products of glucosinolates found primarily in species of Brassicaceae (Cruciferae), are potential anti-cancer compounds. This review compiles data on how through different modes of action ITCs and their synthetic counterparts target leukemia.

Graphical abstractSulforaphane found in broccoli, Brussels sprouts and cabbage induces apoptosis and cell cycle arrest as well as inhibits cell proliferation in leukemic cells.Figure optionsDownload full-size imageDownload as PowerPoint slide