Article ID Journal Published Year Pages File Type
2538815 Fitoterapia 2012 6 Pages PDF
Abstract

Five new furostanol saponins (1–5), together with three known compounds (6–8) were obtained from the n-butanol soluble fraction of ethanol extract from Tupistra chinensis. Their structures were determined on the basis of chemical methods and spectral data. The isolated compounds were tested in vitro for their cytotoxic activities against the A549, HepG 2 and Caski cancer cell lines. Among them, compounds 6, 7, and 8 showed cytotoxicity against A549 cancer cell lines with IC50 values of 6.6, 6.7 and 29.1 μM, respectively.

Graphical abstractFive new furostanol saponins (1–5), together with three known compounds (6–8) were obtained from the rhizomes of Tupistra chinensis.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology
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