Two new triterpenoids from the bark of Eucalyptus exserta and their molluscicidal and cytotoxic activities

Two new triterpenoids, 2α-hydroxyurs-12-en-28-oic acid-3β-trans- isoferulate (1) and 2α, 3α, 24-trihydroxyolean-18-en-28-oic acid (2), together with three known triterpenoids (3–5) were isolated from the methanol extract of the bark of Eucalyptus exserta. Their structures were determined by spectroscopic means. Compounds 1, 2, and 5 exhibited molluscicidal activity against Pomacea canaliculata. All isolated compounds showed significant cytotoxic activity against Spodoptera litura (SL) cells.

Graphic abstractTwo new triterpenoids, 2α-hydroxyurs-12-en-28-oic acid-3β-trans-isoferulate (1) and 2α, 3α, 24-trihydroxyolean -18-en-28-oic acid (2), together with three known triterpenoids (3-5) were isolated from the barks of Eucalyptus exserta. Compounds 1, 2 and 5 showed molluscicidal activities against Pomacea canaliculata. All compounds exhibited significant cytotoxic activities against Spodoptera litura (SL) cells.Figure optionsDownload full-size imageDownload as PowerPoint slide