Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2538852 | Fitoterapia | 2011 | 4 Pages |
Constituents of the fruits of Peatasites tatewakianus were investigated. A new compound, namely bakkenolide-VI (1), was isolated. The structures was elucidated on the basis of 1D, 2D NMR, TOF-MS and ESI-MS techniques, and physicochemical properties. The neuroprotective activity of the new compound was assayed with primary cultured neurons exposed to oxygen–glucose deprivation and oxidative insults.
Graphical AbstractConstituents of the fruits of Peatasites tatewakianus were investigated. A new compound, namely bakkenolide-VI (1), was isolated. The structures was elucidated on the basis of 1D, 2D NMR, TOF-MS and ESI-MS techniques, and physicochemical properties. The new compound exhibited significant neuroprotective and antioxidant activities.Figure optionsDownload full-size imageDownload as PowerPoint slide