A new dimeric resveratrol from the roots of Shorea roxburghii

A new resveratrol dimer, roxburghiol A (1) together with eleven known compounds were isolated from the roots of Shorea roxburghii. Their structures were identified on the basis of spectroscopic evidence and physicochemical properties. All isolated compounds were evaluated for their cytotoxicity (KB and HeLa cells). Compounds 8 and 9 showed potent cytotoxicity against both KB and HeLa cell lines with IC50 values of 6.5, 8.5 and 8.7, 10.1 μg/mL, respectively.

Graphical AbstractA new resveratrol dimer, roxburghiol A (1) together with eleven known compounds were isolated from the roots of Shorea roxburghii. The structures were identified on the basis of spectroscopic evidence and physicochemical properties. All isolated compounds were evaluated for their cytotoxicity against HeLa and KB cells.Figure optionsDownload full-size imageDownload as PowerPoint slide