Three new phenolic compounds from the roots of Glycyrrhiza yunnanensis

Three new phenolic compounds (1–3), together with 16 known compounds (4–19), were isolated from the roots of Glycyrrhiza yunnanensis Cheng f. et L. K. Dai. On the basis of 1D and 2D NMR, HR-ESI-MS, and circular dichroism (CD) spectroscopic analysis, structures of the new compounds were elucidated as 2-(2′-methoxy-4′-hydroxy)-aryl-3-methy-6-hydroxy-benzofuran (1), (2S)-6,7-(2,2-dimethyldihydropyrano)-8-prenyl-4′-hydroxyflavanone (2), and 6-prenyl-7,3′,4′-trihydroxyflavone (3). Compounds 1, 3, 5, 12, 14, 15 and 16 showed antioxidant activity by an ABTS-based assay.

Graphical abstractFigure optionsDownload full-size imageDownload high-quality image (61 K)Download as PowerPoint slide