Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2539006 | Fitoterapia | 2010 | 9 Pages |
The poor and/or erratic oral bioavailability of polyphenolics can be improved using the PHYTOSOME®1 delivery system, a strategy that enhances the rate and the extent of solubilization into aqueous intestinal fluids and the capacity to cross biomembranes. Phospholipids show affinity for polyphenolics, and form supramolecular adducts having a definite stoichiometry. This article reviews the preparation and characterization of PHYTOSOME® complexes and their activity in various medicinal (cardiovascular, anti-inflammatory, hepatoprotective, anticancer) and cosmetic (skin aging) realms of application.
Graphical AbstractsA review about preparation and characterization of PHYTOSOME® complexes and their activity in various medicinal (cardiovascular, anti-inflammatory, hepatoprotective, anticancer) and cosmetic (skin aging) realms of application.Figure optionsDownload full-size imageDownload as PowerPoint slide