| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2539056 | Fitoterapia | 2010 | 5 Pages |
Abstract
The present investigation was carried out with a view to separate bioactive constituent from Aethusa cynapium. Bioactivity guided fractionation of the anxiolytic methanol extract has led to the isolation of a novel unsaturated fatty acid. Structure of the acid characterized by UV, IR, 1H NMR, C13 NMR, MS techniques was found to be trideca-7, 9, 11-trienoic acid. Antianxiety activity was confirmed using the mCPP-induced hypolocomotion test. This new fatty acid—trideca-7,9,11-trienoic acid, isolated from A. cynapium was found to be responsible for the antianxiety activity of the plant.
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Authors
Richa Shri, K.K. Bhutani, Anupam Sharma,