New isoflavonolignan with quinone reductase inducing activity from Alhagi pseudalhagi (M.B.)

Bioassay-directed separation of the chloroform extracts from the air-dried aerial part of Alhagi pseudalhagi (M.B.) led to the isolation of a new isoflavonolignan (1), together with five known isoflavones (2–6) (Fig. 1). Their structures were identified on the basis of spectral analysis of NMR, MS, IR, UV and CD spectral evidences. The quinone reductase (QR) inducing activities of the extracts and compound 1 were evaluated and the new isoflavonolignan (1) exhibited moderate quinone reductase (QR) inducing activity for hepa lclc7 cells.

Graphical abstractBioassay-directed separation of the chloroform extracts from the air-dried aerial part of Alhagi pseudalhagi (M.B.) led to the isolation of a new isoflavonolignan (pseudalhagin A), which exhibited moderate quinone reductase (QR) inducing activity in Hepa lclc7 cells.Figure optionsDownload full-size imageDownload as PowerPoint slide