Constituents from fruits of Cupressus sempervirens

Two new phenolic glycosides (1, 2), along with fourteen known compounds (3–16) have been isolated from the fruit of Cupressus sempervirens. The structures of these compounds were determined by spectroscopic analysis and were evaluated for their inhibitory activity against glycogen phosphorylase and glucose-6-phosphatase enzymes. Compounds 14 showed a moderate inhibition against glucose-6-phosphatase and 15 against glycogen phosphorylase enzymes.

Graphical abstractTwo new phenolic glycosides (1, 2), along with fourteen known compounds (3–16) have been isolated from the fruit of Cupressus sempervirens. Compounds 14 showed moderate inhibition against glucose-6-phosphatase and 15 against glycogen phosphorylase.Figure optionsDownload full-size imageDownload as PowerPoint slide