Article ID Journal Published Year Pages File Type
2539174 Fitoterapia 2010 4 Pages PDF
Abstract

A new secoiridoid named chinensisol (1) along with twenty known compounds were isolated from the 95% ethanol extract of Cortex fraxini. Their structures were elucidated on the basis of NMR, MS, IR and UV spectral evidences. The quinone reductase (QR) inducing activities of the compounds were evaluated and the results showed that compounds 1, 9 and 14 had moderate QR inducing activities with CD values (concentration required to double the specific activity of QR) of 72.4 ± 7.7, 34.3 ± 3.3 and 42.0 ± 0.4 μM respectively.

Graphical abstractA new secoiridoid named chinensisol which showed moderate quinone reductase inducing activity was isolated from Cortex fraxini.Figure optionsDownload full-size imageDownload as PowerPoint slide

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Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology
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