| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2539191 | Fitoterapia | 2010 | 4 Pages |
Abstract
Three new phenolic glycosides, curculigosides F–H (1–3), were isolated from rhizomes of Curculigo orchioides Gaertn. Their structures were elucidated based on comprehensive spectroscopic analyses including IR, MS, 1D- and 2D NMR (HSQC, COSY, and HMBC). Curculigosides F–H (1–3) were evaluated for their anti-HBV activity in vitro using the HBV transfected Hep G2.2.15 cell line. Compound 1 exhibited weak activity with an IC50 value of 2.08 mM on hepatitis B virus (HBV) e antigen (HBeAg) secretion of the HepG2.2.15 cell line.
Graphical abstractFig. 1. The structures of compounds 1–3.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Authors
Ai-Xue Zuo, Yong Shen, Zhi-Yong Jiang, Xue-Mei Zhang, Jun Zhou, Jun Lü, Ji-Jun Chen,