Norlignan derivatives from Curculigo breviscapa

Phytochemical study on the ethanol extract of the rhizomes of Curculigo breviscapa led to the isolation of two new norlignans, breviscapin C (1) and breviscaside B (2), together with six known norlignans, curcapital (3), capituloside (4), pilosidine (5), curcapitoside (6), crassifoside H (7), and crassifoside F (8). Their structures were elucidated on the basis of extensive spectroscopic analysis and comparisons of their data with literature values. All the compounds were isolated for the first time from this plant.

Graphical abstractTwo new norlignans, breviscapin C (1) and breviscaside B (2), together with six known norlignan derivatives, were isolated from the ethanol extract of the rhizomes of Curculigo breviscapa.