Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2539257 | Fitoterapia | 2010 | 4 Pages |
Phytochemical investigation of the fresh bulbs of Fritillaria anhuiensis S. C. Chen et S. E. Yin, resulted in the isolation of a known steroidal alkaloid solanidine of (22S,25S)-solanid-5-en-3β-ol (1), which has never yet been found as a natural substance, and of a new steroidal alkaloid (22S,25S)-solanid-5,20(21)-dien-3β-ol. Compounds 1 and 2 were the first solanidine-type alkaloids with 22-S configuration discovered from nature. Their structures were elucidated based on spectroscopic analysis, including 1D and 2D NMR experiments.
Graphical abstractPhytochemical investigation of the fresh bulbs of Fritillaria anhuiensis S. C. Chen and S. E. Yin, resulted in the isolation of two steroidal alkaloids which were the first solanidine-type alkaloids with 22-S configuration discovered from nature.Figure optionsDownload full-size imageDownload as PowerPoint slide