| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2539259 | Fitoterapia | 2010 | 4 Pages |
Ganoderma lucidum is a traditional medicinal herb used to treat various diseases in China and Southeast Asia for thousands of years. An aqueous glycopeptide, LZ-B-1, was prepared by successive chromatography and exhibited an immunostimulating potential. To better understand the mechanism of bioactivity for this compound, the polysaccharide moiety of glycopeptide LZ-B-1 was studied by NMR spectroscopy. The results indicated that the polysaccharide moiety had a backbone of 1,6-disubstituted-α-galactopyranosyl, 1,2,6-trisubstituted-α-galactopyranosyl, 1,3-disubstituted-β-glucopyranosyl and 1,4,6-trisubstituted-β-glucopyranosyl residues. The branches were mainly composed of 1-substituted-β-glucopyranosyl and 1-substituted-α-fucopyranosyl residues.
Graphical abstractAn aqueous glycopeptide, LZ-B-1, was prepared by successive chromatography and the structure of the polysaccharide moiety of LZ-B-1 was elucidated by NMR spectra.Figure optionsDownload full-size imageDownload as PowerPoint slide
