| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2539300 | Fitoterapia | 2011 | 4 Pages |
Abstract
Activity-guided fractionation of Euphorbia humifusa for anti-HBV activity led to the isolation of two novel sesquiterpenoids, named humifusane A (1) and humifusane B (2). Their structures were elucidated by spectral data to show that they have a caryophyllane-type precursor structure. The two new sesquiterpenoids showed anti-HBV activities through specifically inhibiting the secretion of HBsAg in HepG2.2.15.
Graphical AbstractTwo novel caryophyllane-type sesquiterpenoids, 1 and 2 with anti-HBV activities in vitro, were isolated from the Euphorbia humifusa.Figure optionsDownload full-size imageDownload as PowerPoint slide
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Pharmacology, Toxicology and Pharmaceutical Science
Pharmacology
Authors
Ying Tian, Li-Min Sun, Bin Li, Xi-Qiao Liu, Jun-Xing Dong,