| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2539321 | Fitoterapia | 2010 | 5 Pages |
Polygonum cuspidatum root has been traditionally used for the treatment of dental diseases in Korea. The purpose of this study was to evaluate effects of P. cuspidatum root on the development of dental caries, especially its effects against bacterial viability and caries-inducing factors of Strptococcus mutans and Strptococcus sobrinus. Among methanol extract of P. cuspidatum root and its fraction tested, ethyl acetate fraction, composed of polydatin, resveratrol, anthraglycoside B, and emodin, showed inhibitory effects on glycolytic acid production and glucosyltransferase activity of S. mutans and S. sobrinus in addition to antibacterial activities.
Graphical abstractEthyl acetate fraction, composed of polydatin (1), resveratrol (2), anthraglycoside B (3), and emodin (4), from Polygonum cuspidatum root showed inhibitory effects on glycolytic acid production and glucosyltransferase activity of Strptococcus mutans and Strptococcus sobrinus as well as antimicrobial activities.Figure optionsDownload full-size imageDownload as PowerPoint slide
