A new triglucosylated naphthalene glycoside from Aloe vera L.

A new triglucosylated naphthalene derivative, named aloveroside A (1), together with two known anthraquinone dimers and two 6-phenyl-2-pyrone derivatives, was isolated from the Aloe vera ethanolic extracts. The structure of 1 was established as 1-(((4-(1-O-β-D-glucopyranosyl -(1→4)-β-D-xylopyranoside)-hydroxymethyl)-1-hydroxy-8-O-α-L-rhamnopyranoside)naphthalene-2-yl)-ethanone by means of spectroscopic evidences and chemical methods. All these compounds were tested for their BACE inhibitory activity but no significant activities were found.

Graphical abstractA new triglucosylated naphthalene derivative was isolated from the Aloe vera ethanolic extracts, which was named as aloveroside A (1), and its BACE inhibitory activity was also tested.Figure optionsDownload full-size imageDownload as PowerPoint slide