| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2539418 | Fitoterapia | 2008 | 4 Pages |
Abstract
The 50% ethanolic extracts from 14 plant species used in Thai traditional folklore were screened for cytotoxic activity against a malignant human hepatoma (HepG2) cell line and a normal African green monkey kidney (Vero) cell line. The extracts of Polyalthia evecta and Erythroxylum cuneatum showed potent anticancer activity in the HepG2 cell line with IC50 of 70 ± 3 µg/ml and 64 ± 4 µg/ml, respectively. P. evecta demonstrated more selectivity to the HepG2 than the Vero cell (selectivity index > 14.3) indicating its potential for biopharmaceutical use.
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Authors
P. Prayong, S. Barusrux, N. Weerapreeyakul,