Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2539943 | Fitoterapia | 2007 | 8 Pages |
Abstract
The aqueous leaves extracts of Passiflora alata (100–300 mg/kg, i.p.) and Passiflora edulis (100–1000 mg/kg, i.p.) possess a significant antiinflammatory activity on carrageenan-induced pleurisy in mice. Treatment with the extracts inhibited leukocyte migration and reduced the formation of exudate. Moreover, a significant inhibition of myeloperoxidase and adenosine-deaminase activities was observed at the doses tested (100 or 250 mg/kg, i.p.). At the same doses, a significant decrease of serum C-reactive protein was observed.
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Authors
A.J. Vargas, D.S. Geremias, G. Provensi, P.E. Fornari, F.H. Reginatto, G. Gosmann, E.P. Schenkel, T.S. Fröde,