Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2539944 | Fitoterapia | 2007 | 5 Pages |
Abstract
The Celastrus oil, extracted from seeds of Celastrus paniculatus tested at 2 dose levels (1 and 1.5 g/kg), exhibited significant anxiolytic activity and did not produce tolerance. The non-sedative nature and reversal of buspirone induced behaviour (in open field exploration) point to the serotonergic mechanism underlying the anxiolysis, inspiring further research.
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Authors
Ramamoorthy Rajkumar, Elavarasan Prem Kumar, Suresh Sudha, Bhojraj Suresh,