Article ID Journal Published Year Pages File Type
2539944 Fitoterapia 2007 5 Pages PDF
Abstract

The Celastrus oil, extracted from seeds of Celastrus paniculatus tested at 2 dose levels (1 and 1.5 g/kg), exhibited significant anxiolytic activity and did not produce tolerance. The non-sedative nature and reversal of buspirone induced behaviour (in open field exploration) point to the serotonergic mechanism underlying the anxiolysis, inspiring further research.

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Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology
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