Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2545505 | Journal of Ethnopharmacology | 2013 | 9 Pages |
Abstract
Hydroalcoholic extracts of Terminalia arjuna's stem bark showed antioxidant and antiinflammatory activites. It efficiently scavenged H2O2 induced ROS and attenuated LPS induced TNF-α secretion by monocytes and TNF-α induced cell surface adhesion molecules (VCAM-1 and E-selectin) expression on HAECs.160
Keywords
THP-1Human acute monocytic leukemia cell lineAlcohol extractHAECsLPLVCAM-1IL-8MCP-1ICAM-1LPS3-hydroxy-3-methylglutaryl coenzyme AH2DCFDAHMG-CoA reductaseROSInterleukin-8Terminalia arjunaEndothelial cellshuman aortic endothelial cellsWater extractTNF-αLipoprotein lipaseintercellular adhesion molecule-1Vascular cell adhesion molecule 1Monocytesbutylated hydroxytolueneMonocyte chemotactic protein-1Reactive oxygen species
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Authors
Praveen K. Kokkiripati, Ratnam V. Kamsala, Leena Bashyam, Nalini Manthapuram, Prasanth Bitla, Vidyadhari Peddada, Agepati S. Raghavendra, Sarada D. Tetali,