Article ID Journal Published Year Pages File Type
2547017 Journal of Ethnopharmacology 2009 4 Pages PDF
Abstract

Aim of the studyThis study was performed to examine the effects of tablets containing an extract of Capparis masaikai Levl. (M-tablets) on enhancing oral moisture.Subjects and methodsThe moistening effect of M-tablets was examined in 21 healthy subjects aged 25.1 ± 2.4 (mean ± S.D.) years in comparison with control tablets. After sucking tablets, the oral moisture was measured using a saliva wetness tester and a moisture checker. To evaluate the effects of the M-tablets on oral conditions, additional 50 subjects aged 30.6 ± 7.5 years were examined. The subjects recorded changes in refreshment, oral moisture, ease in speaking, and taste of water using a visual analog scale (VAS).ResultsThe L-SALIVO® value of the M-tablet increased significantly from 1.83 ± 0.17 (mean ± S.E.M.) at baseline to 3.02 ± 0.21 at 15 min (P < 0.01). The Mucus® value of the M-tablet also increased from 37.50 ± 0.22 at baseline to 38.30 ± 0.26 at 15 min (P < 0.01). The VAS value for oral moisture increased significantly from 47.4 ± 2.0 to 69.6 ± 2.2 after taking the M-tablet (P < 0.01). The VAS value for taste of water also increased from 50.0 ± 1.1 to 66.7 ± 3.2 (P < 0.01).ConclusionThese results suggest that M-tablets are useful for enhancing oral moisture, which leads to improvement of oral conditions.

Related Topics
Health Sciences Pharmacology, Toxicology and Pharmaceutical Science Pharmacology
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