| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2547169 | Journal of Ethnopharmacology | 2007 | 7 Pages |
Abstract
The present study was undertaken to investigate the anti-arthritic activity of a biopolymeric fraction (BET) from plant Euphorbia tirucalli Boiss (Euphorbiaceae). The fraction showed dose dependent anti-arthritic activity and also showed in vivo immunomodulatory capacity being a major component in inhibiting arthritis. It caused suppression of CD4+ and CD8+ T cells, inhibition of intracellular Interleukin-2 (IL-2) and Interferon-gamma (IFN-γ) by flowcytometry. It inhibited vascular permeability and the migration of leucocytes at the site of the insult. The oral LD0 in both rats and mice was more than 2000 mg/kg.
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Authors
Sarang Bani, Anpurna Kaul, Beenish Khan, Vijay Kumar Gupta, Naresh Kumar Satti, Krishan Avtar Suri, Ghulam Nabi Qazi,