| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2548509 | Journal of Ethnopharmacology | 2006 | 8 Pages |
Abstract
Devil's Club, Oplopanax horridus (OH), is a widely used folk medicine in Alaska and British Columbia for treating a variety of ailments including arthritis, fever and diabetes. HPLC profiling shows that numerous compounds are present in the 70% ethanolic extract of OH dry root bark powder. OH extract inhibited K562, HL60, MCF7 and MDA-MB-468 cell growth with the 50% inhibition (IC50) estimated at 1/2700, 1/1700, 1/500 and 1/2500 dilutions, respectively. Non-cytotoxic concentrations (
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Authors
Joseph Tai, Susan Cheung, Stefanie Cheah, Edwin Chan, David Hasman,