| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2548646 | Journal of Ethnopharmacology | 2006 | 4 Pages |
Abstract
The ethanol extract of Bacopa monniera (Scrophulariaceae) exhibited marked anti-inflammatory activity against carrageenan-induced paw edema in mice and rats, an acute inflammatory model. To assess the possible mechanism of anti-inflammatory action against carrageenan, the ethanol extract was treated with chemical mediators (histamine, serotonin, bradykinin, prostaglandin E2 and arachidonic acid)-induced edema in rats. The extract selectively inhibited prostaglandin E2-induced inflammation. Thus, it may be inferred that B. monniera possesses significant anti-inflammatory activity that may well be relevant for its effectiveness in the healing of various inflammatory conditions in traditional medicine.
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Authors
Shabana Channa, Ahsana Dar, Shazia Anjum, Muhammad Yaqoob, Atta-ur-Rahman,