Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2549144 | Journal of Pharmacological and Toxicological Methods | 2012 | 11 Pages |
Abstract
Introduction: Numerous studies employing various animal models have found that perinatal stress, encountered in utero during sensitive developmental stages or shortly after birth, disrupts both sexual differentiation and sexual behavior in offspring. The biochemical, cellular, genetic and epigenetic events which are involved in the organismal response to perinatal stress are currently under investigation. Methods, Results and Discussion: In this review, the reader is introduced to perinatal stressors as a toxicological phenomenon, and several recently characterized epigenetic responses to said stressors are discussed.
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Authors
Blase Billack, Ryan Serio, Ilton Silva, Craig H. Kinsley,