| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2549184 | Journal of Pharmacological and Toxicological Methods | 2013 | 9 Pages |
Abstract
In this analysis of archival FFPE samples we were able to identify pathways that are consistent with phenobarbital's mechanism of action. Therefore, we conclude that FFPE samples can be used for meaningful microarray gene expression analyses.
Keywords
thousandRetinoid X receptorRXRPXRlincRNAIPAWTACyPqPCRArchival tissueULslong intergenic non-coding RNAcDNAFFPEQuantitative PCRcomplementary deoxyribonucleic acidRNAribonucleic acidoligostandard deviationOligonucleotideGene expressionIngenuity Pathway AnalysisRINCyanineCytochrome P450DEGRNA Integrity NumberLocally weighted scatterplot smoothingformalin-fixed paraffin-embeddedPhenobarbitalLowessCARpolymerase chain reactionPCRDifferentially expressed geneconstitutive androstane receptorPregnane X receptor
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Authors
A. Francina Jackson, Andrew Williams, Ivy Moffat, Suzanne L. Phillips, Leslie Recio, Michael D. Waters, Iain B. Lambert, Carole L. Yauk,