Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
2549443 | Journal of Pharmacological and Toxicological Methods | 2008 | 11 Pages |
Abstract
Our results show that 1) adrenergic blockade alters the sympathovagal balance; 2) adrenergic blockers enhance the complexity of the cardiac dynamics; 3) the adrenergic blockade effect on cardiac dynamics is primarily the attenuation of small fluctuations in RR intervals. Fractal analysis also has the potential to be applied to early QT diagnosis.
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Authors
Dingzhou Li, Alan Y. Chiang, Christine A. Clawson, Bradley W. Main, Derek J. Leishman,