| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2549965 | Journal of Pharmacological and Toxicological Methods | 2006 | 9 Pages |
Abstract
Nucleic acid based agents require cellular in vitro model systems since they affect the process of gene expression and not the gene product. Hep G2 cells are a useful model to study effects of novel nucleic acid based coagulation inhibitors with an antisense mechanism of action on protein and mRNA level.
Keywords
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Pharmacology
Authors
Markus Böhl, Jürgen Böhl, Bernd Schwenzer,