| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2561606 | Pharmacological Research | 2006 | 8 Pages |
Abstract
Overuse of IPC combination in chronic headache patients is associated with increased plasma levels of indomethacin and caffeine, and with delayed elimination of indomethacin; the high and sustained concentrations of these drugs may cause rebound headache, organ damages, and perpetuate medication-overuse headache.
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Authors
Anna Ferrari, Gustavo Savino, Daniela Gallesi, Diego Pinetti, Alfio Bertolini, Grazia Sances, Ciro Pio Rosario Coccia, Gabriella Pasciullo, Sheila Leone, Marianna Loi, Emilio Sternieri,