| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 2563863 | Pharmacology & Therapeutics | 2008 | 8 Pages |
Abstract
SCREENIT increased the predictability of preclinical results for QTc prolongation without generating any false positive results in class I (13% in class II). Making decisions without isolated heart data increases the risk for eliminating efficient drugs displaying hERG inhibition.
Keywords
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Authors
B.M. Dumotier, M. Deurinck, Y. Yang, M. Traebert, W. Suter,