Zespół jelitowego przerostu bakteryjnego a zapalenie jelit w mukowiscydozie

Massive bacterial colonization of the upper part of the intestine known as small intestinal bacterial overgrowth (SIBO) may significantly influence the function and structure of the digestive system in CF. Available evidence suggests that this condidtion occurs in 30% to 50% of CF patients. Typical symptoms of SIBO, i.e. abdominal discomfort, flatulence, drum belly and gas production are also associated with typical abdominal CF manifestation can be overlooked but may interferre digestion and intestinal absorption. Some data suggest SIBO can cause inflammation in the intestinal tract. In turn, inflammation can stimulate mucin gene expression and mucus secretion. Proper diagnosis and eradication of bacterial overgrowth in the small intestine may improve intestinal function and the general condition of CF patients.