Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
27064 | Journal of Photochemistry and Photobiology A: Chemistry | 2012 | 7 Pages |
A new nonfluorescent benzthiazole derivative of dithio-N-phthaloylglycine was prepared, and its fluorogenic chemodosimetric behaviors toward transition metal ions were investigated. The dithio-N-phthaloylglycine derivative showed highly Hg2+-selective fluorescence enhancing (“turn-on”) properties in 20% aqueous acetonitrile solution (H2O/CH3CN = 80:20, v/v). The chemodosimetric behavior is based on the Hg2+ triggered desulfurization of dithio-N-phthaloylglycine derivative into its oxygen analogue. To observe the cell permeability of 3 into Pollen grains, we also employed it for the fluorescence detection of the changes of intracellular Hg2+ in cultured cells.
Graphical abstractFigure optionsDownload full-size imageDownload as PowerPoint slideHighlights► Non-fluorescent dithio-N-phthaloylglycine derivative showed highly Hg2+-selective turn-on fluorescencent. ► Hg2+-triggered desulfurization utilized for the development of Hg2+-selective chemodosimeter. ► A new amino acid based Hg2+-selective chemodosimeter generates blue fluorescent. ► The sensor was applied for in vivo imaging of Hg2+ using Pollen cells.